The effects of chronic treatment with δ9-tetrahydrocannabinol on catecholamine synthesis in the rat

Autor: Mazurkiewicz-Kwilecki, I. M., Flczewski, M.
Zdroj: Psychopharmacology; March 1973, Vol. 33 Issue: 1 p71-79, 9p
Abstrakt: Chronic administration of d9-tetrahydrocannabinol (2 mg/kg intravenously daily, for one week) to rats resulted in a significant increase in the synthesis of H3-catecholamines in the brain and adrenals. Endogenous noradrenaline and dopamine concentration in the brain, adrenaline and noradrenaline level in adrenals and cardiac noradrenaline content of experimental rats did not differ from those of control animals injected with the solvent alone.
Databáze: Supplemental Index