Effects of psychoactive agents on acquisition of conditioned pole jumping in rats

Autor: Domino, Edward F., Caldwell, Donald F., Henke, Rachel
Zdroj: Psychopharmacology; July 1965, Vol. 8 Issue: 4 p285-289, 5p
Abstrakt: Albino rats required progressively more trials to reach a 90 percent avoidance criterion and achieved less mean total percent avoidance learning than saline injected controls following administration of increasing doses of LSD-25, phencyclidine and amobarbital. The psychotomimetics were effective in depressing acquisition in dosages demonstrated by others to be ineffective in overtrained animals. In contrast d-amphetamine had a slight facilitating effect, but only in large doses.
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