| Autor: |
Krawetz, S. A., Bricker, R. A., Connor, W., Church, R. B., Dixon, G. H. |
| Zdroj: |
TAG Theoretical and Applied Genetics; March 1988, Vol. 75 Issue: 3 p402-409, 8p |
| Abstrakt: |
We have recently cloned both the bovine protamine (Krawetz et al. 1987, DNA 6: 47–57) and high mobility group (HMG-1) cDNAs (Pentecost and Dixon 1984, Bioscience Reports 4: 49–57). They have been used as probes for Restriction Fragment Length Polymorphism analysis of male-female pairs of different species and breeds, within the genus Bos. Utilizing this approach we have studied inheritance, chromosomal location and gene copy number of the bovine protamine and HMG-1 genes. This revealed that these nuclear protein genes are highly conserved suggesting that selective pressure has maintained their gene structures during evolution. A polymorphic Taq 1 restriction fragment was identified that was shown to be a heritable marker. These genes are not sex-linked and are present in a single copy for protamine and at least two copies for the HMG-1. |
| Databáze: |
Supplemental Index |
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