Synthesis and antienzyme activity of 2-OXO-2SR-4-methyl-1,3,2-dioxaphosphorinanes containing salsoline, salsolidine, cytisine, and decahydroquinoline residues

Autor: Dalimov, D. N., Abdullaeva, L. K., Babaev, B. N., Kamaev, F. G., Abduvakhabov, A. A.
Zdroj: Chemistry of Natural Compounds; July 1996, Vol. 32 Issue: 4 p557-560, 4p
Abstrakt: New derivatives of 2-oxo-4-methyl-1,3,2-dioxaphosphorinane containing residues of salsoline, salsolidine, cytisine, and decahydroquinoline have been synthesized, and their antienzyme activities have been investigated. The new compounds are irreversible inhibitors of the ACNE, BuChE, and CBE of warm-blooded animals and of insects: the antienzyme activities of the compounds depend substantially on the structure of the alkaloid component of the inhibitor molecule.
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