19-Norsteroids. Preparation of acetates of 5α-halo-6β,19-oxidoandrostan-3β-ol-17-one

Autor: Maksimov, B. I., Lur'i, F. A., Samsonova, N. V., Morozova, L. S.
Zdroj: Pharmaceutical Chemistry Journal; February 1970, Vol. 4 Issue: 2 p63-67, 5p
Abstrakt: Conditions were found for oxidation of the 3-acetate of 5a-bromoandrostan-3?,6?-diol-17-one with lead tetraacetate from which the pure acetate of 5a-bromo-6?,19-oxidoandrostan-3?-ol-17-one could be obtained in 87–89 % yield. It was shown that the technical product obtained under these conditions can be used without purification for further transformations.
Databáze: Supplemental Index