| Abstrakt: |
The interactions between biological objects (proteins, cells, bacteria,?...) and surfaces play a major role in life sciences, particularly for biomedical applications. The present paper is focused on the nanometer scale of these interactions. Nano-structured surfaces, from either a chemical or a topographical point of view, can be considered as good tools to analyze such interactions. Hence, some aspects dealing with: (i) the adsorption of proteins onto self-organized molecular surfaces or other nano-structured surfaces, (ii) bacterial adhesion onto polymeric nano-organized surfaces, (iii) cell and bacterial adhesion onto surfaces exhibiting a controlled nano-topographical and chemical structure (patterned surfaces, dense array of nano-beads, ...), are briefly presented and discussed. Les interactions entre les objets biologiques (prot?ines, cellules, bact?ries, ...) et les surfaces jouent un r?le primordial en sciences du vivant, dans le domaine biom?dical notamment. Le pr?sent texte est plus particuli?rement focalis? sur l'?chelle nanom?trique de ces interactions. Des surfaces nanostructur?es, tant du point de vue chimique que topographique, sont de bons outils pour analyser de telles interactions. Ainsi, quelques aspects concernant : (i) l'adsorption de prot?ines sur des surfaces mol?culaires auto-organis?es ou autres surfaces nanostructur?es, (ii) l'adh?sion bact?rienne sur des surfaces polym?res nano-organis?es, (iii) l'adh?sion cellulaire et bact?rienne sur des surfaces ? nanotopographie et chimie contr?l?es (surfaces pattern?es, arrangement compact de nanobilles, ...), sont bri?vement pr?sent?s et discut?s. |
