Immunocytochemical evidence for SV40-related T antigen in two human brain tumours of ependymal origin

Autor: Tabuchi, K., Kirsch, W. M., Van Buskirk, J. J.
Zdroj: Acta Neurochirurgica; September 1978, Vol. 43 Issue: 3-4 p239-249, 11p
Abstrakt: Summary A series of thirty-nine human brain tumours has been screened for the presence or absence of SV40-related T antigen by the direct and indirect immunoperoxidase techniques. Two tumours (an ependymoma and a choroid plexus papilloma) of ependymal origin revealed markedly positive nuclear staining for T antigen both in in vivo and in vitro. The possible viral etiology of these human brain tumours is discussed in relation to recent human papovavirus isolates.
Databáze: Supplemental Index