Degradation of β-lactam antibiotics by polyacrylamide-entrapped β-lactamase-producingE. coli cells

Autor: Pache, W.
Zdroj: Applied Microbiology and Biotechnology; September 1978, Vol. 5 Issue: 3 p171-176, 6p
Abstrakt: Cells of a ß-lactamase producingE. coli strain were immobilized with acrylamide and lyophilized. The gel particles containing the entrapped cells were used like an immobilized enzyme to study the inactivation of ß-lactam antibiotics. The substrate profile of the ß-lactamase was determined and the action of ß-lactamase inhibitors studied.
Databáze: Supplemental Index