Degradation of β-lactam antibiotics by polyacrylamide-entrapped β-lactamase-producingE. coli cells
Autor: | Pache, W. |
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Zdroj: | Applied Microbiology and Biotechnology; September 1978, Vol. 5 Issue: 3 p171-176, 6p |
Abstrakt: | Cells of a ß-lactamase producingE. coli strain were immobilized with acrylamide and lyophilized. The gel particles containing the entrapped cells were used like an immobilized enzyme to study the inactivation of ß-lactam antibiotics. The substrate profile of the ß-lactamase was determined and the action of ß-lactamase inhibitors studied. |
Databáze: | Supplemental Index |
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