| Autor: |
Finogenova, T. V., Shishkanova, N. V., Ermakova, I. T., Kataeva, I. A. |
| Zdroj: |
Applied Microbiology and Biotechnology; February 1986, Vol. 23 Issue: 5 p378-383, 6p |
| Abstrakt: |
The ability of the wild Candida lipolytica strain and its two mutants with the modified glyoxylate cycle to synthesize citric and isocitric acids in media with various carbon sources (glucose, glycerol, hexadecane, acetate, ethanol) was studied. The mutant with high isocitrate lyase and low aconitate hydratase activities was shown to synthesize citric acid almost exclusively when grown on any of the above mentioned carbon sources. The other mutant with low isocitrate lyase and high aconitate hydratase activities produced primarily isocitric acid in media with n-alkanes. Isocitrate lyase inhibition by itaconate in the wild strain shifted acid synthesis towards predominant isocitrate synthesis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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