Kinetics of amine-inhibited naphthalene hydroxylation by rat liver microsomal cytochrome P-450

Autor: Akhrem, A. A., Usanov, S. A., Metelitsa, D. I.
Zdroj: Reaction Kinetics and Catalysis Letters; September 1976, Vol. 5 Issue: 3 p359-366, 8p
Abstrakt: Inhibition constants for amine-inhibited naphthalene hydroxylation by rat liver microsomal cytochrome P-450 have been determined. Irrespective of the nature of the amine added, inhibition has a competitive character. The inhibition mechanism of cytochrome P-450 dependent hydroxylation is discussed.
Databáze: Supplemental Index