| Autor: |
Wike-Hooley, J. L., Faithfull, N. S., Zee, J., Berg, A. P. |
| Zdroj: |
European Journal of Applied Physiology; August 1983, Vol. 51 Issue: 2 p269-279, 11p |
| Abstrakt: |
The role of hepatic oxygenation in causing liver damage during treatment with whole body hyperthermia (WBHT) was investigated, following observations that this toxicity was not related to the maximum core temperature or the heat dose administered. Measurement of hepatic blood flow during WBHT was attempted in four patients, using continuous infusion of indocyanine green (ICG). The flow values obtained were unrealistically large, in two cases more than half the cardiac output, due to considerable decreases in ICG extraction during treatment. The two patients with the greatest liver function changes were also those in whom the most hepatic damage was seen following treatment. Plasma disappearance of ICG following treatment was also abnormal in all patients. |
| Databáze: |
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