Prevalence of pertussis IgG antibodies in children in Palermo, Italy

Autor: Stroffolini, T., Giammanco, A., Taormina, S., Nisticò, L., Chiarini, A., De Crescenzo, L., Cascio, A., Lupo, F., Nicosia, V., Torres, G., Valenza, A. R.
Zdroj: Infection; September 1989, Vol. 17 Issue: 5 p280-283, 4p
Abstrakt: Summary The prevalence of IgG antibodies toBordetella pertussis in a sample of 615 1–12-year-old unvaccinated children in Palermo was estimated by ELISA. The overall prevalence was 56%; it increased from 24% in one to three-year-old children to 67% in 11–12-year-old children (p<0.01). IgG antibody prevalence was not associated with the father's years of schooling (OR 1), nor with the family size (OR 1.3; C.I. 95%=0.8-2.2). For children aged one the three years, serological results showed that the history of pertussis reported by parents in questionnaires gave high specificity (93.2%) and negative predictive value (85.4%). Our seroepidemiological study evidences a great exposure of children toB. pertussis in Palermo, with a high proportion of infections occurring after three years of age.
Databáze: Supplemental Index