| Autor: |
Parry, S. H., Boonchai, S., Abraham, S. N., Salter, J. M., Rooke, D. M., Simpson, J. M., Bint, A. J., Sussman, M. |
| Zdroj: |
Infection; March 1983, Vol. 11 Issue: 2 p123-128, 6p |
| Abstrakt: |
Summary The distribution of mannose-resistant (MRHA) and mannose-sensitive (MSHA) fimbrial haemagglutinins was examined in 482 strains ofEscherichia coli isolated from 390 adult women and 45 pregnant mothers with a variety of urinary tract infections (UTI), and from 47 healthy controls. The proportion of MRHA strains was significantly higher in patients with symptomatic UTI (75%) than in women with non-significant bacteriuria (30%, p<0.001), pregnant women with asymptomatic UTI (34%, p<0.001) and healthy controls (0%). The proportion of MSHA strains was significantly lower in patients with symptomatic UTI (22%) than in women with non-significant bacteriuria (46%, p<0.001) and pregnant women with asymptomatic UTI (52%, p<0.01). Only 17% of the strains from healthy controls had MSHA activity. In pregnant women with UTI, whether this was symptomatic or asymptomatic, there was a significant association between infection with MRHA strains ofE. coli and a past history of UTI. Thus, in a pregnant woman with an infection and a past history of UTI there is a seven-fold greater chance that this infection is due to an MRHA-bearing organism than in pregnant women without such a history. There was also a significant association between MRHA organisms and symptomatic infection. The risk of symptomatic patients having an infection with an MRHA strain is six times greater than that for a patient with a covert infection. |
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