Autor: |
Ibsen, Kenneth H., Urist, Marshall R., Uyeno, Satsuki, Sanders, Russell L. |
Zdroj: |
Calcified Tissue International; December 1967, Vol. 1 Issue: 1 p243-245, 3p |
Abstrakt: |
By exposing hydroxyapatite crystals of a regulated mesh size to increasing concentrations of citrate or oxytetracycline, it was possible to arrive at a constant saturation value for the ratio of ligand to calcium of hydroxyapatite in the resultant solid phase. When both ligands were present in a single solution, each reduced the amount of the other that was bound per unit quantity of calcium of the hydroxyapatite. A column chromatographic separation of citrate from oxytetracycline that permitted quantitative determination of citrate when both are present in a solution is described in this communication. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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