(3H]MK-801 binding sites in postmortem brain regions of schizophrenic patients

Autor: Kornhuber, J., Mack-Burkhardt, F., Riederer, P., Hebenstreit, G. F., Reynolds, G. P., Andrews, H. B., Beckmann, H.
Zdroj: Journal of Neural Transmission; June 1989, Vol. 77 Issue: 2-3 p231-236, 6p
Abstrakt: Summary [3H]MK-801 binding was used as a marker for the NMDA receptor-ion channel complex in postmortem brain samples from the frontal cortex, hippocampus, putamen, entorhinal region, and amygdala of schizophrenic patients and controls. In schizophrenia [3H]MK-801 binding levels were increased in all brain regions investigated reaching significance in the putamen.
Databáze: Supplemental Index