Dimensions of the ion channel in neuronal nicotinic acetylcholine receptor as estimated from analysis of conformation-activity relationships of open-channel blocking drugs

Autor:	Zhorov, Boris S., Brovtsyna, Nina B., Gmiro, Valeriy E., Lukomskaya, Nera Ya., Serdyuk, Sergei E., Potapyeva, Natalva N., Magazanik, Lev G., Kurenniy, Dmitriy E., Skok, Vladimir I.
Zdroj:	Journal of Membrane Biology; April 1991, Vol. 121 Issue: 2 p119-132, 14p
Abstrakt:	Summary Relationship between the size of the molecule in the series of organic ions Et3N-(CH2)5-N+R1R2R3 (Ri-alkyl or cycloalkyl substituents) and their abilities to block nicotinic acetylcholine receptors (AChRs) due to their open-channel blockade in the neurons of autonomic ganglia and in frog end-plate was analyzed.
Databáze:	Supplemental Index
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