| Autor: |
Mehta, Prashant P., Ramasarma, T., Ramakrishna Kurup, C. K. |
| Zdroj: |
Molecular and Cellular Biochemistry; September 1990, Vol. 97 Issue: 1 p75-85, 11p |
| Abstrakt: |
Intraperitoneal administration of the nontoxic silicon compound, 1-ethoxysilatrane, to the rat did not cause proliferation of hepatic mitochondria or of endoplasmic reticulum, nor did it affect mitochondrial oxidative phosphorylation. The activities of cholesterol 7 a-hydroxylase in hepatic microsomes and of cholesterol oxidase in mitochondria respectively were unaffected by silatrane treatment. The rate of release of bile, whose composition remained unchanged, also was not increased in silatrane-treated animals. The results indicated that the compound did not affect the pathway of cholesterol degradation. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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