| Autor: |
McLaren, John D., Chu, Ernest H. Y. |
| Zdroj: |
Molecular and Cellular Biochemistry; September 1983, Vol. 57 Issue: 2 p167-175, 9p |
| Abstrakt: |
The synergistic effects of potential amino donors were studied in the assay of CTP synthetase in extracts of Chinese hamster fibroblasts. We found that L-glutamine was not effective as the sole amino donor, but combinations of L-glutamine with NH4HCO3, L-arginine or potassium phosphate did result in the conversion of UTP to CTP. L-arginine or potassium phosphate were also not effective when used alone, and NH4HCO3 was only slightly effective. Our studies demonstrate that the individual synergistic combinations were not additive; multiple combinations of components decreased rather than increased the formation of CTP. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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