| Autor: |
Plessis, P., Lamy, T., Donnio, P. Y., Autuly, F., Grulois, I., Le Prisé, P. Y., Avril, J. L. |
| Zdroj: |
European Journal of Clinical Microbiology & Infectious Diseases; November 1995, Vol. 14 Issue: 11 p959-963, 5p |
| Abstrakt: |
Vancomycin-resistant enterococci have been isolated with increasing frequency since 1988. Thus far, most of these resistant enterococci have belonged to theEnterococcus faecium species, and epidemiological studies have shown a wide diversity among inter-hospital and intrahospital isolates. This report presents an epidemiologic investigation of 25 vancomycin-resistantEnterococcus strains — 24Enterococcus faecium and oneEnterococcus gallinarum — isolated from the stools or blood of adult patients receiving intravenous vancomycin prophylaxis during neutropenia and hospitalized in a single hematologic unit. Macrorestriction patterns of total DNA and of ribosomal DNA regions were used to analyze the strains. Strains produced different total DNA restriction fragment length polymorphism patterns after Smal digestion. Ribotyping was less discriminative than pulsed-field gel electrophoresis. The results confirmed the genetic unrelatedness of the strains. Prolonged vancomycin administration, commonly used in hematologic units, could be involved in the selection of endogenous resistant enterococcal strains. |
| Databáze: |
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