| Autor: |
Al-Orainey, I. O., Gad El Rab, M. O., Al-Hajjaj, M. S., Saeed, E. S. |
| Zdroj: |
European Journal of Clinical Microbiology & Infectious Diseases; January 1992, Vol. 11 Issue: 1 p58-61, 4p |
| Abstrakt: |
An enzyme immunoassay (EIA) for the detection of mycobacterial antigens in sputum was evaluated. The system utilises commercially available anti-BCG immunoglobulin. BCG protein standard was used as positive control. Thirty-nine patients with culture-proven pulmonary tuberculosis were tested. The EIA was positive in 24 of 29 patients with positive smears and cultures, giving a sensitivity of 86.2 %. It was also positive in six of ten patients with smear-negative culture-positive disease, resulting in a sensitivity of 60 % in this group. In another 176 patients with different nontuberculous pulmonary infections, only nine were positive by EIA, giving a specificity of 94.9 %. The high sensitivity and specificity of the assay make it a useful tool for the early diagnosis of pulmonary tuberculosis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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