| Autor: |
Vanmali, A. N., Lentnek, A. L., Franco, J., Ngwenya, B. Z. |
| Zdroj: |
European Journal of Clinical Microbiology & Infectious Diseases; June 1983, Vol. 2 Issue: 3 p206-212, 7p |
| Abstrakt: |
A restrospective single blind study was conducted to compare the efficacy of crossed-immunoelectrophoresis using concanavalin A intermediate gel with double immunodiffusion tests in the diagnosis of invasive candidiasis. On the basis of cytoplasmic antibody detection, crossed-immunoelectrophoresis with concanavalin A differentiated reliably betweenCandida albicans fungemia and invasive candida infection, whereas double immunodiffusion did not. With regard to sensitivity, specificity, and predictive value crossed-immunoelectrophoresis with concanavalin A was superior to double immunodiffusion. Analysis of double immunodiffusion precipitin bands revealed fuzzy and sharp precipitin bands which corresponded to mannan (fuzzy) and cytoplasmic (sharp) antibodies in the crossed-immunoelectrophoresis with concanavalin A assay. Therefore, the finding of sharp bands in the double immunodiffusion procedure supports the diagnosis of invasive candidiasis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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