In vivo distribution studies of radioactively labelled platinum complexes; cis-dichlorodiammine platinum(II), cis-trans-dichlorodihydroxy-bis-(isopropylamine) platinum (IV), cis-dichloro-bis-cyclopropylamine platinum(II), and cis-diammine 1,1-cyclobutanedicarboxylate platinum(II) in patients with malignant disease, using a gamma camera

Autor: Owens, S., Thatcher, N., Sharma, H., Adam, N., Harrison, R., Smith, A., Zaki, A., Baer, J., McAuliffe, C., Crowther, D., Fox, B.
Zdroj: Cancer Chemotherapy and Pharmacology; April 1985, Vol. 14 Issue: 3 p253-257, 5p
Abstrakt: Summary The in vivo distribution in man of the four platinum derivatives cis-dichlorodiammine platinum(II) (DDP), cis-trans-dichlorodihydroxy-bis-(isopropylamine) platinum (IV) (CHIP), cis-dichloro-bis-cyclopropylamine platinum (II) (CP), and cis-diammine 1,1-cyclobutanedicarboxylate platinum(II) (CBDCA) has been observed. The availability of these compounds labelled with the radioactive isotope of platinum, platinum-191, has made serial in vivo imaging of their distribution possible.
Databáze: Supplemental Index
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