An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells

Autor: Ben-Nun, Avraham, Strauss, William, Leeman, Sara A., Cohn, Lauren E., Murre, Cornelis, Duby, Allan, Seidman, J. G., Glimcher, Laurie H.
Zdroj: Immunogenetics; March 1985, Vol. 22 Issue: 2 p123-130, 8p
Abstrakt: In this report we present data demonstrating the endogenous expression of I-region associated (la) antigens on a cloned line of mouse T cells, CTLL, as well as transcription of the invariant chain gene in these cells. We demonstrate further that this Ia-bearing T-cell clone, CTLL, can utilize the expressed la molecules to present antigen to la-restricted antigen-specific T cells.
Databáze: Supplemental Index