| Autor: |
Eardley, D. D., Murphy, D. B., Kemp, J. D., Shen, F. W., Cantor, H., Gershon, R. K. |
| Zdroj: |
Immunogenetics; December 1980, Vol. 11 Issue: 1 p549-557, 9p |
| Abstrakt: |
An I-J-subregion controlled determinant is expressed on Ly-1 inducer and Ly-1,2 acceptor T cells in the feedback suppression circuit. Ly-1 T cells absorb the I-J antibody reactive with the Ly-1,2 acceptor T cell, suggesting that both inducer and acceptor T cells have the same 1-J determinant. Since less than 10 percent of Ly-1 or Ly-1,2 T cells are killed by anti-I-J plus complement treatment, the I-J determinant demarcates functionally distinct subsets of both the Ly-1 and Ly-1,2 T-cell sets. This I-J determinant is not expressed on a detectable number of Ly-1 helper T cells which induce B lymphocytes to produce anti-sheep red cell antibody in tissue culture. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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