Asymmetry of salivary gland I123 Metaiodobenzylguanidine (MIBG) uptake in a patient with cervical neuroblastoma and Horner's syndrome-possible etiologic mechanisms

Autor: Sandler, E. D., Hattner, R. S., Parisi, M. T.
Zdroj: Pediatric Radiology; June 1992, Vol. 22 Issue: 3 p225-226, 2p
Abstrakt: Horner's syndrome may be due to a variety of serious underlying disorders including cervical neuroblastoma. Horner's syndrome results from a unilateral disruption of the sympathetic innervation to the head and neck. We report a patient with cervical neuroblastoma in whom post operative metaiodobenzylguanidine (MIBG) scans showed a striking decrease in uptake in the ipselateral salivary glands. Since the biodistribution of I123 metaiodobenzylguanidine in the salivary glands in also dependent on sympathetic innervation, the presence of Horner's syndrome can be reflected in the MIBG scan.
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