| Autor: |
Mithani, Sabena D., Bakatselou, Vassiliki, TenHoor, Christopher N., Dressman, Jennifer B. |
| Zdroj: |
Pharmaceutical Research; January 1996, Vol. 13 Issue: 1 p163-167, 5p |
| Abstrakt: |
Purpose. The objective of this study was to develop a model to predict the extent to which bile salts can enhance the solubility of a drug, based on the physicochemical properties of the compound. The ability to predict bile salt solubilization of poorly soluble drugs would be a key component in determining which drugs will exhibit fed vs. fasted differences in drug absorption. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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