Autor: |
Berry, Gerard, Yandrasitz, John R., Segal, Stanton |
Zdroj: |
Neurochemical Research; January 1982, Vol. 7 Issue: 1 p49-54, 6p |
Abstrakt: |
Abnormal myo-[2-3H]inositol incorporation into phosphatidylinositol has been found in phentolamine-treated synaptosomes that were isolated from the cerebral hemispheres of galactose toxic rats and incubated with [33P]Pi and myo-[2-3H] inositol. In galactose toxic rats phentolamine-stimulated myo-[2-3H]inositol labeling of phosphatidylinositol was 70% greater than in normal animals. This enhanced labeling of synaptosomal phosphatidylinositol in galactose toxic rats during stimulation with phentolamine is in marked contrast to the depressed myo-inositol labeling of phosphatidylinositol reported with acetylcholine stimulation. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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