Molecular analysis of foot-and-mouth disease type O viruses isolated in Saudi Arabia between 1983 and 1995

Autor: *, A. R. SAMUEL, ‡, KNOWLES, N. J., KITCHING, R. P., HAFEZ, S. M.
Zdroj: Epidemiology and Infection; December 1997, Vol. 119 Issue: 3 p381-389, 9p
Abstrakt: Partial nucleotide sequence of the capsid polypeptide coding gene 1D (VP1) was determined for 68 serotype O foot-and-mouth disease viruses isolated between 1983 and 1995 from outbreaks occurring in Saudi Arabia. The sequences were compared with previously published sequences: 14 viruses of Middle Eastern origin (isolated between 1987 and 1991); and with four vaccine virus strain sequences, three originating from the Middle East (O1/Turkey/Manisa/69, O1/Sharquia/Egypt/72 and O1/Israel/2/85) and one from Europe (O1/BFS 1860/UK/67). The virus isolates from Saudi Arabia and the Middle East vaccine virus strains formed a related genetic group distinct from the European O1virus. Within this large group 12 distinct genetic sublineages were observed.
Databáze: Supplemental Index