| Autor: |
Turpaev, T. M., Yuzhanskaya, M. G. |
| Zdroj: |
Neuroscience and Behavioral Physiology; October 1973, Vol. 6 Issue: 4 p369-375, 7p |
| Abstrakt: |
Illumination of frog heart muscle, vitally stained with eosin (10-4-10-6 M) reduces myocardial sensitivity to acetylcholine (AC) and, to a lesser degree, to choline. Acetylcholine (10-7-10-6 M) and imidazole derivatives (e.g., histidine 10-4 M) prevent photoinactivation of heart muscle sensitivity to AC. It is postulated that photoinactivation of the sensitivity of the myocardium to AC is the result of inactivation of cholinergic receptors and that the imidazole ring is a component of the esterophilic point of the active center of the cholinergic receptor. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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