Heterozygosity in inbred strains of the tree-hole mosquitoAedes triseriatus

Autor: Matthews, T. C., Craig, G. B.
Zdroj: Biochemical Genetics; October 1987, Vol. 25 p647-655, 9p
Abstrakt: Inbred stocks of the tree-hole mosquitoAedes triseriatus from four localities were developed using full-sib mating. The progress of inbreeding was followed electrophoretically at eight variable and six less variable enzyme loci. Rates of fixation of several of these loci were substantially lower than expected. Discrepancies between observed and expected fixation values were evident in the early stages of inbreeding and became larger as inbreeding progressed.Odh, Hbd, Pgm, andHk-4 were usually not fixed. By the F12 and F14 generations of brother-sister mating, most individuals in the two lines were heterozygotes (Odh andHbd in the TK lines andOdh, Hbd, Pgm, andHk-4 in the TV lines). The probability of maintaining heterozygosity at several selectively neutral and unlinked loci simultaneously is very low.Odh, Hbd, Pgm, andHbd loci are linked to lethal recessives on chromosome 2, creating a balanced lethal system which in turn accounts for the heterozygosity in these inbred mosquitoes.
Databáze: Supplemental Index