| Autor: |
Morcos, N. C., Gardin, J. M., Tomita, N., Henry, W. L. |
| Zdroj: |
Basic Research in Cardiology; September 1992, Vol. 87 Issue: 5 p437-451, 15p |
| Abstrakt: |
Normal aging in man is known to be associated with a reduction in left-ventricular diastolic function, including the rates of relaxation and filling. Calcium channel blockers have been reported to improve left-ventricular diastolic function in patients with various forms of heart disease. Clinically, the action of calcium channel blockers may be related to either a direct myocardial effect or may be secondary to the peripheral or coronary vasodilation effects. The purpose of this study is to investigate a possible direct effect of calcium channel blockers on modulation of the reported age-related reduction in myocardial relaxation. |
| Databáze: |
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