Autor: |
Regitz, V., Paulson, D. J., Hodach, R. J., Little, S. E., Schaper, W., Shug, A. L. |
Zdroj: |
Basic Research in Cardiology; March 1984, Vol. 79 Issue: 2 p207-217, 11p |
Abstrakt: |
Summary The effects of 3 hours of ischemia and 1 hour of reperfusion on biochemical, physiological and ultrastructural parameters were studied in 12 dogs. In the ischemic subendocardium without reperfusion, mitochondrial losses of adenine (ATP+ADP+AMP) and pyridine (NAD+NADH) nucleotides far exceeded those observed in whole tissue. Adenine nucleotide translocator (aNT) was severely inhibited and seemed to, be a sensitive indicator of a lesion of the inner mitochondrial membrane. |
Databáze: |
Supplemental Index |
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