| Autor: |
Montz, W. Edward, Kirkpatrick, Roy L. |
| Zdroj: |
Archives of Environmental Contamination and Toxicology; January 1985, Vol. 14 Issue: 1 p19-24, 6p |
| Abstrakt: |
Brain cholinesterase (ChE) activities were determined for white-footed mice (Peromyscus leucopus) orally dosed with either diazinon (18.8 mg/kg body weight) or parathion (10 mg/kg body weight). Following treatment with diazinon, a latent period of approximately six hr elapsed during which time ChE activity was relatively unaffected. After the latent phase, ChE activity rapidly declined to a minimum 12 hr after dosing. After 48 hr, ChE activity recovered to levels only slightly below that of the controls. The response of both male and female white-footed mouse brain ChE to dosing with parathion was similar to that exhibited by animals dosed with diazinon. ChE activities declined rapidly at 6 hr and reached a minimum 24 hr after dosing. ChE activity of treated animals was comparable to that of controls 48 hr after treatment. Brain ChE activities of treated female white-footed mice were significantly lower (P<0.05) than those of treated males. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Full text from SpringerLink