Changes in renal efferent activity and autonomic response to GABA applied to structures of the ventrolateral surface of the cat medulla oblongata

Autor: Shapoval, L. N., Pobegailo, L. S.
Zdroj: Neurophysiology; May 1987, Vol. 19 Issue: 3 p240-247, 8p
Abstrakt: Effects of injecting 1 µl 1·10-5–5·10-4 M gamma-aminobutyric acid (GABA) into the neuronal structures of the chemically sensitive area of the bulbar ventrolateral surface and clearly-defined borders of this area with GABA-sensitive cells were investigated in cats anesthetized by a mixture of chloralose and urethane. It was found that GABA, interacting with bicuculline-sensitive GABAa receptors, exercises an inhibitory effect on the activity of neuronal structures of the ventrolateral surface involved in governing blood pressure, heart rate, and vascular tonus.
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