Electron probe X-ray analysis of siderosomes in haemarthrotic articular cartilage

Autor: Ghadially, F. N., Oryschak, A. F., Ailsby, R. L., Mehta, P. N.
Zdroj: Virchows Archiv B Cell Pathology Zell-pathologie; December 1974, Vol. 16 Issue: 1 p43-49, 7p
Abstrakt: Past studies have indicated that in the haemarthrotic joint haemosiderin deposits occur in the synovial membrane but not in articular cartilage. We have demonstrated, (1) by electron probe x-ray analysis that iron deposits do occur in chondrocytes, (2) by electron microscopy that such deposits lie in single membrane bound lysosomal bodies called siderosomes and (3) by light microscopic histochemistry that when conditions are suitable these deposits give both the Prussian blue and Turnbull’s blue reaction for iron. These findings are consistent with the idea that haemosiderin deposits occur in chondrocytes from haemarthrotic joints.
Databáze: Supplemental Index