Detection and characterization of the tetracycline resistance determinant, tetM, inHaemophilus ducreyi

Autor: Johnson, Steven R., Biddle, James W., DeWitt, Wallis E.
Zdroj: Current Microbiology; July 1989, Vol. 19 Issue: 1 p7-12, 6p
Abstrakt: A single tetracycline- and penicillin-resistant isolate ofHaemophilus ducreyi was shown by hybridization to contain the streptococcal tetracycline resistance determinant TetM. TetM was not plasmid-borne but was located in the bacterial chromosome. Restriction analysis of thetetM gene with two probes derived from a clonedtetM gene indicated that it was duplicated inH. ducreyi and that both copies of thetetM gene were intact.
Databáze: Supplemental Index