Serodiagnosis of infection withTrypanosoma evansi in camels in the Sudan

Autor: Luckins, A., Boid, R., Rae, P., Mahmoud, M., Malik, K., Gray, A.
Zdroj: Tropical Animal Health and Production; February 1979, Vol. 11 Issue: 1 p1-12, 12p
Abstrakt: Five diagnostic tests for infection withTrypanosoma evansi have been compared in groups of camels experimentally infected or exposed to natural infection in the Sudan. The correlation of positive results obtained by assays of IgM levels, the mercuric chloride test and the formol gel test with the presence of active infection was unsatisfactory, but there was a good correlation between results obtained using IFAT and ELISA and proven infection. Sera from a high proportion of apparently uninfected camels from endemic areas gave positive reactions with all 5 tests, possibly indicating inadequate parasitological diagnosis or persistence of antibody after unsatisfactory chemotherapy. It was concluded that serological tests using trypanosomal antigens to detect antibodies were more sensitive for diagnosis than indirect tests based on raised euglobulin levels. Serodiagnostic tests may therefore have a place in future programmes for surveillance and control ofT. evansi infections in camels.
Databáze: Supplemental Index