| Autor: |
Raeman, F., De Cock, W., De Beukelaar, T., Leempoels, J., De Cree, J., Verhaegen, H. |
| Zdroj: |
Clinical Rheumatology; September 1982, Vol. 1 Issue: 3 p194-198, 5p |
| Abstrakt: |
Summary The number of T-lymphocytes and T-lymphocyte subsets was measured in peripheral blood of 51 patients with rheumatoid arthiritis. T-lymphocytes were counted by E-rosette tests and by the immunogold staining method with OKT3.PAN monoclonal antibody. Helper and suppressor T-lymphocytes were determined by the immunogold staining method with OKT4.IND and OKT8.SUP monoclonal antibody. The relative and absolute numbers of T-lymphocytes and helper T-lympohocytes in peripheral blood of patients with RA did not differ significantly from those in the blood of healthy subjects. However, the relative and absolute numbers of suppressor T-cells were significantly lower in patients with RA than in healthy subjects. The decrease of suppressor T-cells in the blood of patients with RA dit not correlate with the activity of the disease nor the presence of the rheumatoid factor. |
| Databáze: |
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