Cell kinetics and hormonal features in relation to pathological stage in breast cancer

Autor: Amadori, Dino, Bonaguri, Chiara, Nanni, Oriana, Gentilini, Patrizia, Lundi, Nadia, Zoli, Wainer, Riccobon, Angela, Vio, Antonio, Magni, Enrico, Saragoni, Ariele
Zdroj: Breast Cancer Research and Treatment; March 1991, Vol. 18 Issue: 1 p19-25, 7p
Abstrakt: Proliferative activity (expressed as3H-thymidine labeling index,3H-TdR LI) was evaluated on a series of 281 primary tumors recruited in two years in 6 different institutions from central Italy.3H-TdR LI proved to be low in intraductal, or well and moderately differentiated, or hormone receptor positive tumors. Conversely, no relation was observed between3H-TdR LI and menopause, tumor size, or lymph node involvement. An inverse relation was observed between3H-TdR LI and hormone receptor content. Specific patterns of3H-TdR LI value and ER content association were observed as a function of menopause, lymph nodal status, and degree of lymph nodal involvement.
Databáze: Supplemental Index