Characterization and mapping of DNA sequence homologous to mouse U1a1 snRNA: Localization on chromosome 11 near theDlb-1 andRe loci

Autor: Michael, Simon K., Hilgers, Jo, Kozak, Christine, Whitney, J. Barry, Howard, Eugene F.
Zdroj: Somatic Cell and Molecular Genetics; May 1986, Vol. 12 Issue: 3 p215-223, 9p
Abstrakt: A phage clone which contained a functional U1a1snRNA gene was isolated from a mouse genomic library. A single copy fragment was isolated from the 3' flanking region of the U1a1gene and used as a hybridization probe for Southern blotted DMAs from recombinant inbred strains of mice, mouse-hamster hybrid cells, and the offspring from backcrosses between BALB/c mice and mice which were heterozygous for the Rex (Re)marker. The results of these experiments prove that the U1a1gene is located on chromosome 11 near the Delb-1and Reloci.
Databáze: Supplemental Index