| Autor: |
Maconochie, Mark K., Brown, Stephen D. M., Greenfield, Andrew J. |
| Zdroj: |
Mammalian Genome; March 1991, Vol. 2 Issue: 1 p64-68, 5p |
| Abstrakt: |
We have isolated two genomic clones from the murine dystrophin locus, containing single exons encoding protein sequence from the putative actin-binding domain of the amino-terminus and the terminal portion of the triple helical domain. Using interspecific backcross progeny mice, both clones were shown to be X-linked. Sequence analysis indicated that the amino-terminal clone contains a 173 bp exon exhibiting 90% nucleotide sequence identity to human dystrophin exon 6, whilst the C-terminal clone contains a 61 bp exon with 93% nucleotide sequence identity to the human cDNA sequence. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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