Efficacy of oral sotalol in reentrant ventricular tachycardia

Autor: Obel, I. W. P., Jardine, R., Haitus, B., Scott Millar, R. N.
Zdroj: Cardiovascular Drugs and Therapy; June 1990, Vol. 4 Issue: Supplement 3 p613-618, 6p
Abstrakt: Summary Oral sotalol was given to 64 patients (78% postinfarction) with recurrent, reentrant ventricular tachycardia (VT) during an average follow-up period of 19.7 months. Fifty-nine (92%) patients had previously experienced recurrent ventricular tachycardia, in spite of having received an average of three conventional antiarrhythmic drugs (13 had previously failed on other Class III drugs). The nature and mechanism of the VT was proved with electrophysiologic testing (EPS), and the chronic sotalol dosage was determined by repeated EPS at 3- to 4-day intervals until the VT was no longer inducible.
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