| Autor: |
Ibrahim, T. M., Unger, P. H., Sobolski, J., Depelchin, P., Jottrand, M., Degre, S. |
| Zdroj: |
Cardiovascular Drugs and Therapy; July 1989, Vol. 3 Issue: 4 p557-561, 5p |
| Abstrakt: |
Summary To assess the hemodynamic effects of SIN-1, the active metabolite of the venodilator molsidomine, after acute as well as chronic intravenous administration, ten patients with exacerbation of chronic heart failure were studied. After a mean bolus dose of 2 mg of SIN-1, mean right atrial pressure (MRAP), mean pulmonary artery pressure (MPAP), and pulmonary capillary wedge pressure (PCAP) decreased significantly up to the 60th minute; pulmonary vascular resistance (PVR) decreased significantly up to the 30th minute, while cardiac index (CI) and systemic vascular resistance (SVR) remained unchanged. |
| Databáze: |
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| Externí odkaz: |
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