| Autor: |
Depelchin, P., Sobolski, J., Jottrand, M., Flament, C. |
| Zdroj: |
Cardiovascular Drugs and Therapy; November 1988, Vol. 2 Issue: 1 p139-147, 9p |
| Abstrakt: |
Therapeutic interventions in patients with myocardial infarction, whether during the first hours after coronary occlusion or several days later, aim to reduce mortality and morbidity by several mechanisms: Prevention of fatal ventricular fibrillation, limitation of infarct size, and inhibition of platelet aggregation are some examples of such mechanisms. Results from early intervention trials with beta blocking agents, particularly from ISIS-I, suggest that 1-year mortality is significantly lower in selected patients randomized to active treatment. Late intervention studies also suggest a significant reduction in coronary mortality and morbidity with beta blockade, particularly when data are pooled. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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