Some features of nucleo-cytoplasmic RNA transport from isolated nuclei

Autor: Peskin, A. V., Koen, Y. M., Zbarsky, I. B.
Zdroj: Molecular Biology Reports; May 1981, Vol. 7 Issue: 1-3 p25-30, 6p
Abstrakt: Messenger RNA is released preferentially from isolated rat liver nuclei in the presence of the ATP-generating system and cytosol. The release is suppressed by spermidine, while cytoplasmic RNase inhibitor was ineffective and PCMB like some other thiol-blocking agents inhibitory. Cytoplasmic SOD added to the system strongly suppressed RNA release. A similar effect could be obtained by anaerobiosis due to addition of SMP. In both cases the inhibition is reversed by cyanide.
Databáze: Supplemental Index