| Autor: |
McCloud, T G, Burns, M P, Majadly, F D, Muschik, G M, Miller, D A, Poole, K K, Roach, J M, Ross, J T, Lebherz, W B |
| Zdroj: |
Journal of Industrial Microbiology and Biotechnology; July 1995, Vol. 15 Issue: 1 p5-9, 5p |
| Abstrakt: |
Fermentation conditions are described for the production of the antitumor antibiotic 7-(S)-brefeldin-A (brefeldin-A) in liquid culture byEupenicillium brefeldianum, (B. Dodge) Stolk and Scott, ATCC 58665. An analytical hplc method was developed which allowed rapid quantitation of the compound during fermentation. A kilogram of brefeldin-A was isolated from a fermentation at the 6800-liter scale. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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