| Autor: |
Driessens, F. C. M., Ramselaar, M. M. A., Schaeken, H. G., Stols, A. L. H., Mullem, P. J., Wijn, J. R. |
| Zdroj: |
Journal of Materials Science: Materials in Medicine; November 1992, Vol. 3 Issue: 6 p413-417, 5p |
| Abstrakt: |
Sintered microporous cylinders of hydroxyapatite (OHA), tertiary calcium phosphate (ß-TCP and rhenanite (CaNaPO4) were implanted in the bone of the forehead of the domestic pig (Sus scrofa). Implants together with the surrounding bone were retrieved after 6 and 12 weeks. X-ray diffraction showed that OHA and ß-TCP maintain their crystal structure upon implantation. However, rhenanite is transformed completely into an apatite within 6 weeks. This apatite later incorporates sodium and carbonate. Both ß-TCP and rhenanite implants showed some resorption but were otherwise covered with new bone. Electron microprobe analysis showed that the mineral at the interface had a Ca/P ratio characteristic of new bone. At a certain distance from the interface lower Ca/P ratios were found, characteristic of precursor phases of bone mineral. This suggests that the deposition of new bone starts, at least partially, from the surface of the implant. Therefore, ß-TCP as well as rhenanite may be called an osteoconductive biomaterial. |
| Databáze: |
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