Morpholinylanthracyclines: cytotoxicity and antitumor activity of differently modified derivatives

Autor: Ripamonti, Marina, Capolongo, Laura, Melegaro, Giulia, Gornati, Carlo, Bargiotti, Alberto, Caruso, Michele, Grandi, Maria, Suarato, Antonino
Zdroj: Investigational New Drugs; June 1996, Vol. 14 Issue: 2 p139-146, 8p
Abstrakt: The relationship between different chemical modifications on morpholinylanthracyclines and their ability to overcome multidrug resistance (MDR) has been evaluated testing all compounds in vitro on LoVo and LoVo/DX human colon adenocarcinoma cells and in vivo on disseminated P388 and P388/DX murine leukemias.
Databáze: Supplemental Index