| Autor: |
Einzig, Avi I., Lipsitz, Stuart, Wiernik, Peter H., Benson, Al. B. |
| Zdroj: |
Investigational New Drugs; September 1995, Vol. 13 Issue: 3 p223-227, 5p |
| Abstrakt: |
Taxol was administered as a 24-hour continuous infusion at 250 mg/m2 in this Phase II trial in patients with adenocarcinomas of the upper gastrointestinal tract (UGIT). Twenty-five patients were entered between July 1991 and June 1992, twenty-three were eligible and were evaluated for toxicity and twenty-two were assessable for response. There was one partial response (4.5%) in a patient with liver metastases, with a duration of 6 months. Toxicity was primarily neutropenia. Taxol as a single agent appears to have little activity in adenocarcinoma of the UGIT. |
| Databáze: |
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