| Autor: |
Green, Michael D., Speyer, James L., Wernz, James C., Colombo, Nicoletta, Beller, Uziel, Muggia, Franco M., Beckman, E. Mark |
| Zdroj: |
Investigational New Drugs; August 1990, Vol. 8 Issue: 3 p333-336, 4p |
| Abstrakt: |
Sixteen patients with metastatic ovarian cancer who had not previously been treated with anthracyclines were treated with 4' deoxydoxorubicin at a dose of 30 mg/m2 intravenously every 3 weeks. There were no clinical responses in this group of patients. Toxicities were infrequent with neutropenia and thrombocytopenia being dose limiting. Nausea and vomiting occurred in only 4 patients. We conclude that 4' deoxydoxorubicin is an inactive drug in this patient population and does not warrant further investigation in this disease. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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